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Updated: Aug 11, 2026

Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine
Published on: February 17, 2018
[Autonomic status and neurohumoral regulation in patients with refractory tachyarrhythmia]
Abstract:
Results are submitted of vegetative testing as well as of studying the 24.h excretion of catecholamines, activity of cholinesterase, the levels of thyroxin, triiodothyronine and hydrocortisone in blood plasma of 120 patients with tachyarrhythmias that do not respond to antiarrhythmic drug preparations. The functional state of the vegetative nervous system in the attack-free period in the above patients was mostly determined by hyperfunction of its sympathetic subdivision in the presence of inadequate vegetative reactivity, frequently excessive, occasionally weakened, and instability of adrenergic and cholinergic influences. It is suggested that augmented secretion of the hormones studied might be of compensatory nature.
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