Related Experiment Videos
[Relationship between properties of 131I therapy and radioiodine kinetics]
K Schomäcker1, U Wellner, K Scheidhauer
1Klinik und Poliklinik für Nuklearmedizin, Universität zu Köln, Deutschland.
Aim:
The reason of unreproducible data under diagnosis and therapy with radioiodine should be elucidated.
Methods:
The iodine content of the capsules was tested by a colorimetric method and by activation analysis. Radiochemical purity was determined by HPLC and by electrophoresis. Solubility of the capsules was investigated under different conditions.
Results:
The iodine content of the capsules varied between 0.8 and appr. 100 micrograms/capsule. The radiochemical purity of the capsule iodine varied between 75% and 99.5% (main contamination: iodate). The solubility of the capsules differed.
Conclusion:
Additional non-radioactive iodine in the therapy capsules could be one reason of the reduced radioiodine-uptake under therapy.