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Merkel cell carcinoma in Israel
B Brenner1, A Katz, E Rakowski
1Institute of Oncology, Rabin Medical Center, Petah Tikva, Israel.
Israel Journal of Medical Sciences
|December 1, 1996
Summary
Merkel cell carcinoma, a rare skin cancer, was studied in Israel. Findings show it affects older adults, typically on sun-exposed skin, with a 58% 3-year survival rate.
Area of Science:
- Oncology
- Dermatology
- Epidemiology
Background:
- Merkel cell carcinoma (MCC) is a rare, highly malignant skin cancer.
- Limited data exists on MCC's clinical and epidemiologic characteristics in Israel.
Purpose of the Study:
- To report the first clinical and epidemiologic characteristics of Merkel cell carcinoma in Israel.
- To compare findings with international data and identify unique population-specific features.
Main Methods:
- Retrospective analysis of Merkel cell carcinoma cases in Israel.
- Collection of data on patient demographics, disease characteristics, and outcomes.
Main Results:
- Average age at diagnosis was 69 years, with equal sex distribution.
- MCC predominantly occurred on sun-exposed skin, with a 3-year survival rate of 58%.
- Unique findings included a predominance of Ashkenazic Jews and a high rate of second malignancies.
Conclusions:
- Findings are largely consistent with international MCC data.
- Predominance in Ashkenazic Jews and increased second malignancy rates are notable.
- Increased awareness of this aggressive skin cancer in Israel is crucial.