Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Dilated cardiomyopathy and thrombo-embolism

J Günthard1, F Stocker, D Bolz

  • 1University Children's Hospital, Barno, Switzerland.

European Journal of Pediatrics
|January 1, 1997
PubMed
Summary

Children with dilated cardiomyopathy and reduced left ventricular function face a high risk of thrombo-embolism. Prophylactic anticoagulation is recommended for those with fractional shortening below 20% to prevent serious complications.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Quadriceps or triceps surae proprioceptive neuromuscular facilitation stretching with post-stretching dynamic activities does not induce acute changes in running economy.

Frontiers in physiology·2022
Same author

Scintillation light detection in the 6-m drift-length ProtoDUNE Dual Phase liquid argon TPC.

The European physical journal. C, Particles and fields·2022
Same author

Prospects for beyond the Standard Model physics searches at the Deep Underground Neutrino Experiment: DUNE Collaboration.

The European physical journal. C, Particles and fields·2021
Same author

Oxygen consumption of gastrocnemius medialis muscle during submaximal voluntary isometric contractions with and without preceding stretch.

Scientific reports·2017
Same author

Does postexercise modelled capillary blood flow accurately reflect cardiovascular effects by different exercise intensities?

Clinical physiology and functional imaging·2017
Same author

[Whether or not to perform an early endoscopy following ingestion of potentially caustic agents - a retrospective longterm analysis in a tertiary referral institution].

Zeitschrift fur Gastroenterologie·2016

Area of Science:

  • Pediatric Cardiology
  • Cardiovascular Research
  • Hematology

Background:

  • Dilated cardiomyopathy in children is associated with significant morbidity.
  • Thrombo-embolism is a serious complication in pediatric patients with heart conditions.

Purpose of the Study:

  • To determine the incidence, outcomes, and prevention strategies for thrombo-embolism in pediatric patients diagnosed with dilated cardiomyopathy.
  • To assess the relationship between left ventricular systolic function and thrombo-embolic events.

Main Methods:

  • Retrospective analysis of 130 pediatric patients with dilated cardiomyopathy.
  • Evaluation of thrombo-embolic events, including cardiac thrombus, embolus, and autopsy findings.
  • Comparison of left ventricular fractional shortening (FS) between patients with and without thrombo-embolism.

Related Experiment Videos

Main Results:

  • Thrombo-embolism occurred in 17% (14%) of pediatric patients with dilated cardiomyopathy.
  • Patients with thrombo-embolism exhibited significantly impaired left ventricular systolic function (FS 10% +/- 3%) compared to those without (FS 17% +/- 6%, P < 0.0001).
  • Anticoagulant treatment showed a trend towards reducing further embolic events.

Conclusions:

  • Children with dilated cardiomyopathy and fractional shortening below 20% are at high risk for thrombo-embolic events.
  • Prophylactic anticoagulative therapy should be considered for these high-risk pediatric patients.
  • Early identification and management of thrombo-embolism are crucial for improving outcomes in pediatric dilated cardiomyopathy.