Pediatric intracranial hemangioendotheliomas: case report
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T C Chen1, I Gonzalez-Gomez, F H Gilles
1Division of Neurosurgery, Children's Hospital of Los Angeles, California, USA.
Objective And Importance:
Intracranial hemangioendotheliomas are rare lesions, especially in the pediatric age group. Recognizing hemangioendotheliomas as a differential in intracranial tumors of vascular origin is important; complete excision results in a cure, and medical therapy for those lesions that are not resectable produces long-term survival.
Clinical Presentation:
We report two patients, a 7-year-old female patient with a lesion in the right gasserian ganglion and a 3-month-old male patient with a cervicomedullary junction tumor.
Intervention:
The 7-year-old underwent a gross total removal with no recurrence. The 3-month-old underwent a partial resection followed by treatment with interferon alpha-2a, with a decrease in the size of the residual tumor. Both patients have been followed for more than 4 years without a recurrence or progression of the tumor.
Conclusion:
Hemangioendotheliomas are fairly indolent tumors and may be treated with complete surgical resection, resulting in a cure. In cases in which complete tumor removal is not possible, adjunctive therapy with interferon alpha-2a may control residual tumor growth.