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[Bone marrow aplasia related to ticlopidine]
J P de Jaureguiberry1, M Galzin, P Talard
1Service de médecine interne-oncologie, hôpital d'instruction des Armées Sainte-Anne, Toulon, France.
Abstract:
The authors report two cases of bone marrow aplasia observed 2 months after initiation of a treatment with ticlopidine. The outcome was favorable after discontinuation of therapy. The frequency of this severe drug-induced complication seems to have been underestimated. The absolute necessity of a careful haematological survey during the first 3 months of therapy is pointed out.