[Cerebrovascular reactivity in the pathogenesis of ischemic brain lesions in patients of different ages]

Cerebrovascular indices (cerebrovascular reactivity, plethora of pulse, the degree of atherosclerotic damage of carotids) were evaluated in 445 patients with either transient disturbances of brain's circulation or ischemic stroke. The patients' age was 32-85 years. It was found that the alterations in the system of neurogenic regulation which were the consequences of some pathogenic factors' influence (infectious diseases, closed brain's trauma, latent intoxication), resulted in some cases in formation of lower level of cerebrovascular reactivity which in turn was one of the reasons of ischemic cerebral disorder development. Further influence of such factors as atherosclerosis, increase of blood coagulability, decrease of total arterial pressure may result in alterations in cerebrovascular system's stability and in development of cerebrovascular diseases at younger age.