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Coronary thrombosis associated with inherited protein S deficiency: a case report
1Department of Cardiology, Harry S. Truman Memorial VA Hospital, Columbia, MO 65201, USA.
Heart & Lung : the Journal of Critical Care
|January 1, 1997
Insights
Protein S deficiency (PSD) can increase the risk of blood clots, like deep vein thrombosis. This case highlights a young man with PSD experiencing acute myocardial infarction due to coronary thrombosis.
Area of Science:
- Cardiovascular Medicine
- Hematology
Background:
- Protein S deficiency (PSD) is a known risk factor for thrombotic events.
- Venous thrombosis, both superficial and deep, are commonly associated with PSD.
Observation:
- A young male patient presented with symptoms suggestive of an acute cardiac event.
- Diagnostic workup revealed the patient had Protein S deficiency.
Findings:
- The patient experienced acute myocardial infarction (heart attack).
- The myocardial infarction was caused by thrombosis within the coronary arteries.
- This coronary thrombosis was linked to the patient's underlying Protein S deficiency.
Implications:
- This case underscores that Protein S deficiency can manifest as arterial thrombosis, specifically coronary thrombosis.
- It highlights the importance of considering PSD in young individuals presenting with myocardial infarction.
- Further research may explore the spectrum of thrombotic events associated with PSD.
Abstract:
Protein S deficiency (PSD) may be associated with thrombotic events, including venous and arterial thrombosis. Most commonly, superficial and deep venous thrombosis have been noted. We report a case of acute myocardial infarction resulting from coronary thrombosis in a young male with PSD.