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[Brain tumor and parkinsonism]

T Kondo1

  • 1Department of Neurology, Juntendo University School of Medicine.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|January 1, 1997
PubMed
Summary

Brain tumors, particularly meningiomas, can cause parkinsonism. Early symptoms mimic Parkinson's disease, but atypical signs like visual defects indicate a tumor-related cause.

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Area of Science:

  • Neurology
  • Neuro-oncology

Context:

  • Parkinsonism is a neurological condition characterized by motor symptoms similar to Parkinson's disease.
  • Brain tumors can present with diverse neurological deficits, including parkinsonian features.

Purpose:

  • To review and analyze reported cases of parkinsonism associated with brain tumors.
  • To identify common tumor types and locations linked to parkinsonism.
  • To differentiate tumor-induced parkinsonism from idiopathic Parkinson's disease.

Summary:

  • Parkinsonism can arise from various brain tumors, with sphenoid ridge or frontal convexity meningiomas being most frequent.
  • While early symptoms resemble Parkinson's disease, atypical signs like visual field defects and motor weakness are characteristic.
  • Pathogenesis likely involves nigrostriatal system dysfunction due to chronic mechanical compression by the tumor.

Impact:

  • Highlights the importance of considering brain tumors in the differential diagnosis of parkinsonism.
  • Aids in recognizing atypical presentations that may suggest a neoplastic cause.
  • Informs diagnostic strategies for patients presenting with parkinsonian symptoms.

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