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Repeat hepatic resection for recurrent colorectal cancer
Q D Chu1, M P Vezeridis, K A Avradopoulos
1Department of Surgery, Brown University School of Medicine, Roger Williams Medical Center, 825 Chalkstone Avenue, Providence, Rhode Island 02908-4735, U.S.A.
World Journal of Surgery
|March 1, 1997
Summary
Repeat liver resection for colorectal cancer metastases is a viable option for selected patients. This procedure offers a low risk and can improve survival for those with limited liver recurrence.
Area of Science:
- Hepatobiliary Surgery
- Colorectal Cancer Metastasis
- Surgical Oncology
Background:
- Hepatic resection is standard for colorectal cancer liver metastases.
- Recurrence in the liver after initial resection is common, affecting two-thirds of patients.
- Data on repeat liver resection for recurrence are limited.
Observation:
- A review of 10 patients (9 evaluable) who underwent repeat hepatic resection for colorectal cancer liver metastases.
- Indications for repeat surgery included elevated carcinoembryonic antigen (CEA) and constitutional symptoms.
- The average interval between the first and second resection was 21 months.
Findings:
- One surgical death occurred due to hepatic failure after a trisegmentectomy.
- Estimated 1- and 5-year survival rates from the second resection were 78% and 23%, respectively.
- Median survival was 41 months from the first resection and 16 months from the second.
Implications:
- Repeat hepatectomy for recurrent liver metastases is a feasible option for carefully selected patients.
- This surgical approach is associated with low risk.
- Repeat liver resection can potentially enhance survival in patients with well-defined, liver-limited metastases.