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The NRSub database: update 1997

G Perrière1, I Moszer, T Gojobori

  • 1Laboratoire de Biométrie, Génétique et Biologie des Populations, Université Claude Bernard, Lyon 1, 43, bd. du 11 Novembre 1918, 69622 Villeurbanne Cedex, France. perriere@biomserv.uni-lyon1.fr

Nucleic Acids Research
|January 1, 1997
PubMed
Summary
This summary is machine-generated.

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A new non-redundant database, NRSub, was created for Bacillus subtilis genome sequencing. It offers curated, annotated sequences with cross-references, improving data accessibility for researchers.

Area of Science:

  • Genomics
  • Bioinformatics
  • Microbial Databases

Background:

  • The international project aims to sequence the entire Bacillus subtilis genome.
  • Existing sequence repositories contain redundant and unannotated data.

Purpose of the Study:

  • To develop NRSub, a non-redundant database for Bacillus subtilis sequences.
  • To enhance sequence data with comprehensive annotations and cross-references.

Main Methods:

  • Collected Bacillus subtilis sequences from public repositories.
  • Identified and removed sequence duplications.
  • Added gene accession numbers, genetic map locations, and codon usage indices.
  • Integrated cross-references with EMBL/GenBank/DDBJ, MEDLINE, SWISS-PROT, and ENZYME databases.

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Main Results:

  • NRSub provides a curated, non-redundant set of Bacillus subtilis sequences.
  • Enhanced annotations and cross-references improve data utility.
  • The database is accessible via anonymous FTP and dedicated World Wide Web servers.

Conclusions:

  • NRSub serves as a valuable resource for Bacillus subtilis research.
  • The database facilitates easier access to high-quality genomic information.
  • NRSub supports ongoing and future genomic studies of Bacillus subtilis.