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Database on the structure of large ribosomal subunit RNA
P De Rijk1, Y Van de Peer, R De Wachter
1Departement Biochemie, Universiteit Antwerpen (UIA), Universiteitsplein 1, B-2610 Antwerpen, Belgium.
Nucleic Acids Research
|January 1, 1997
Summary
The updated large ribosomal subunit RNA database now includes 429 aligned sequences with secondary structure information. Researchers can access this valuable ribosomal RNA (rRNA) data via a web server or anonymous FTP.
Area of Science:
- Molecular Biology
- Bioinformatics
Background:
- Ribosomal RNA (rRNA) databases are crucial for understanding cellular machinery.
- The large ribosomal subunit RNA is a key component of ribosomes.
Purpose of the Study:
- To announce the latest release of the large ribosomal subunit RNA database.
- To highlight the accessibility and features of the associated rRNA WWW Server.
Main Methods:
- Compilation and alignment of 429 large ribosomal subunit RNA sequences.
- Incorporation of secondary structure information for all sequences.
- Development of a new query interface for the rRNA WWW Server.
Main Results:
- The database now contains 429 aligned large ribosomal subunit RNA sequences.
- Secondary structure information is integrated into the sequence data.
- The rRNA WWW Server offers enhanced data retrieval through a new query interface and anonymous FTP access.
Conclusions:
- The updated database and enhanced server provide a more accessible and informative resource for researchers studying ribosomal RNA.
- The integrated secondary structure information aids in detailed analysis of rRNA.