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Related Experiment Videos

REBASE-restriction enzymes and methylases

R J Roberts1, D Macelis

  • 1New England BioLabs, 32 Tozer Road, Beverly, MA 01915, USA. roberts@neb.com

Nucleic Acids Research
|January 1, 1997
PubMed
Summary
This summary is machine-generated.

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REBASE is a comprehensive database for restriction enzymes and methylases, detailing recognition sites, cleavage sites, and availability. This valuable resource is accessible through various digital channels for researchers worldwide.

Area of Science:

  • Biochemistry
  • Molecular Biology
  • Bioinformatics

Background:

  • Restriction enzymes and methylases are crucial tools in molecular biology.
  • Databases are essential for organizing and accessing complex biological information.
  • REBASE has historically served as a key resource for these enzymes.

Purpose of the Study:

  • To provide an overview of the REBASE database.
  • To highlight the scope of information contained within REBASE.
  • To detail the accessibility of REBASE for researchers.

Main Methods:

  • Information compilation on restriction enzymes and methylases.
  • Data organization including recognition and cleavage sites.
  • Dissemination of information through electronic mailings, anonymous ftp, WAIS/gopher, and the World Wide Web.

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Main Results:

  • REBASE offers comprehensive data on restriction enzymes and methylases.
  • Information includes recognition sites, cleavage sites, and commercial availability.
  • Specialized files compatible with various software packages are provided.

Conclusions:

  • REBASE is a vital, up-to-date resource for researchers working with restriction enzymes and methylases.
  • The database's accessibility ensures broad utility in molecular biology and related fields.
  • REBASE facilitates research by providing readily usable data for bioinformatics tools.