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The bm12 Inducible Model of Systemic Lupus Erythematosus (SLE) in C57BL/6 Mice
Published on: November 1, 2015
Systemic lupus erythematosus with membranous glomerulonephritis and uterine vasculitis
S Feriozzi1, A O Muda, M Amini
1Divisione di Nefrologia e Dialisi e Anatomia ed Istologia Patologica, Ospedale Grande degli Infermi, Azienda USL/Vt, Viterbo, Italy.
Abstract:
We report a case of lupus vasculitis with uterine localization and concurrent membranous nephropathy. Immunofluorescence study suggested the occurrence of an immune complex nephropathy and a pauci-immune pathogenesis of vasculitis. Our case points out the event of tissue damage in two organs mediated by different pathogenetic mechanisms. In addition, uterine vasculitis without pregnancy may be observed in patients with systemic lupus erythematosus nephritis.
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