Ifosfamide combined with toremifene in the treatment of non-small cell lung cancer
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Published on: October 27, 2014
E R Salomaa1, K Liippo, J Ellmen
1Turku University Hospital, Department of Pulmonary Diseases and Clinical Allergology, Preitilä, Finland.
Abstract:
The efficacy and safety of toremifene-ifosfamide as a first-line chemotherapy in non-small cell lung cancer were assessed. Sixteen patients were treated with oral toremifene (420 mg on days 1-4 and 240 mg on day 5) followed by ifosfamide infusion 5 g/m2 on day 5 every 3 weeks 1-6 times. Toremifene at the doses used did not enhance the effect or toxicity of ifosfamide in previously untreated non-small cell lung cancer patients.
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