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Related Experiment Videos

Asthma pharmacotherapy: current practices and outlook

H W Kelly1

  • 1College of Pharmacy, School of Medicine, University of New Mexico Health Sciences Center, Albuquerque 87131, USA.

Pharmacotherapy
|January 1, 1997
PubMed
Summary

Asthma is a growing public health issue. New guidelines recommend inhaled corticosteroids, but concerns about side effects and cost persist, leading to exploration of alternatives like combination therapies and newer asthma medications.

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Area of Science:

  • Pulmonary Medicine
  • Public Health
  • Pharmacology

Background:

  • Asthma presents a significant public health challenge in the US due to high incidence, increasing prevalence, and substantial economic costs.
  • Current pharmacologic treatments for asthma vary in efficacy and cost.
  • Recent guidelines advocate a four-step approach based on disease severity and symptom control, emphasizing anti-inflammatory agents like inhaled corticosteroids.

Purpose of the Study:

  • To review current asthma management guidelines and physician prescribing patterns.
  • To explore alternative therapeutic strategies to high-dose corticosteroid use in asthma management.

Main Methods:

  • Analysis of recently published asthma management guidelines.
  • Observation of shifts in physician prescribing patterns for asthma medications.

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  • Review of alternative pharmacologic options beyond corticosteroids.

    • Main Results:

    • Physician prescribing patterns show some adoption of new asthma guidelines.
    • Concerns regarding potential adverse effects and cost of corticosteroids influence treatment decisions.
    • Combination therapy with long-acting bronchodilators and newer agents like leukotriene modifiers are emerging as alternatives.

    Conclusions:

    • While guidelines are being adopted, reluctance to use corticosteroids persists due to safety and cost concerns.
    • Alternative asthma management strategies, including combination therapies and novel medications, offer promising options.
    • Further research into the long-term efficacy and safety of these alternatives is warranted.