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Malignant tumors of the heart and great vessels: MR imaging appearance
M T Mader1, T B Poulton, R D White
1Department of Diagnostic Radiology, Aultman Hospital, Canton, OH 44710, USA.
Insights
Primary heart and great vessel tumors are rare but serious. Magnetic resonance (MR) imaging is the preferred diagnostic tool due to its detailed visualization and assessment capabilities for these cardiovascular tumors.
Area of Science:
- Cardiovascular Imaging
- Oncology
- Radiology
Background:
- Primary tumors of the heart and great vessels are uncommon, presenting with nonspecific symptoms like chest pain and dyspnea.
- Common types include angiosarcoma, malignant fibrous histiocytoma, high-grade sarcomas, and paraganglioma, often involving pericardial and myocardial invasion.
Purpose of the Study:
- To highlight the diagnostic advantages of magnetic resonance (MR) imaging for primary cardiac and great vessel tumors.
- To compare MR imaging with other modalities like echocardiography and computed tomography.
Main Methods:
- Review of the capabilities of MR imaging in diagnosing and assessing primary heart and great vessel tumors.
- Discussion of specific MR techniques such as multiplanar imaging, cine-loop acquisition, and perfusion assessment.
- Mention of the role of gadolinium-based contrast agents in tumor enhancement.
Main Results:
- MR imaging offers superior multiplanar visualization of cardiac, pericardial, mediastinal, and pulmonary structures.
- It provides enhanced morphologic differentiation between tumor and surrounding tissues.
- Dynamic imaging and perfusion assessment aid in diagnosis and treatment response evaluation.
Conclusions:
- Magnetic resonance imaging is the imaging modality of choice for primary tumors of the heart and great vessels.
- Its comprehensive capabilities facilitate accurate diagnosis, staging, and monitoring of treatment response.
- MR imaging plays a crucial role in the management of these rare cardiovascular malignancies.
Abstract:
Fortunately, primary tumors of the heart and great vessels are rare. These primary tumors include angiosarcoma, malignant fibrous histiocytoma, high-grade and pleomorphic sarcoma, and paraganglioma with pericardial and myocardial invasion. Symptoms are often nonspecific and include chest pain and dyspnea. Although these tumors are often diagnosed with echocardiography and computed tomography, magnetic resonance (MR) imaging currently appears to be the imaging modality of choice because of its diverse capabilities, which include multiplanar imaging for excellent anatomic definition of the heart, pericardium, mediastinum, and lungs; improved morphologic differentiation between tumor tissue and surrounding cardiovascular, mediastinal, or pulmonary tissues; dynamic imaging with a gated cine-loop acquisition; and assessment of tissue perfusion. The use of gadopentetate dimeglumine is helpful in achieving tumor enhancement on MR images but is not required. MR imaging is also useful in assessing tumor response to surgery, radiation therapy, and chemotherapy.
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