Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Biological mediators of insect immunity

J P Gillespie1, M R Kanost, T Trenczek

  • 1Department of Biochemistry, Kansas State University, Manhattan 66506, USA.

Annual Review of Entomology
|January 1, 1997
PubMed
Summary

Insects mount a robust immune defense against pathogens using specialized cells and secreted proteins. This response involves pathogen recognition, cellular encapsulation, and the production of antimicrobial peptides.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Protease inhibitors of Manduca sexta expressed in transgenic cotton.

Plant cell reports·2013
Same author

An immunoglobulin binding protein (antigen 5) of the stable fly (Diptera: Muscidae) salivary gland stimulates bovine immune responses.

Journal of medical entomology·2008
Same author

Bacterial challenge stimulates innate immune responses in extra-embryonic tissues of tobacco hornworm eggs.

Insect molecular biology·2004
Same author

Overview of parasitism associated effects on host haemocytes in larval parasitoids and comparison with effects of the egg-larval parasitoid Chelonus inanitus on its host Spodoptera littoralis.

Journal of insect physiology·2003
Same author

cDNA cloning, purification, properties, and function of a beta-1,3-glucan recognition protein from a pyralid moth, Plodia interpunctella.

Insect biochemistry and molecular biology·2003
Same author

Identification by subtractive suppression hybridization of bacteria-induced genes expressed in Manduca sexta fat body.

Insect biochemistry and molecular biology·2003

Area of Science:

  • * Insect immunology
  • * Invertebrate defense mechanisms

Background:

  • * Insect immune responses involve complex cellular and molecular mechanisms.
  • * Pathogen recognition relies on hemolymph proteins binding to microbial polysaccharides.
  • * Hemocytes are crucial for cellular immunity, performing phagocytosis and forming aggregates or capsules.

Purpose of the Study:

  • * To elucidate the multifaceted insect immune response to infection.
  • * To highlight the roles of hemocytes and antimicrobial proteins.
  • * To explore the regulation of immune gene expression.

Main Methods:

  • * Review of existing literature on insect immune responses.
  • * Analysis of cellular interactions and molecular pathways involved in defense.
  • * Examination of protein synthesis and secretion in response to pathogens.

Main Results:

  • * Diverse hemocyte types cooperate to isolate and eliminate pathogens.
  • * Phenoloxidase activation and antimicrobial peptide synthesis are key components.
  • * Insect immune gene regulation shares similarities with mammalian acute phase responses.

Conclusions:

  • * Insects possess sophisticated innate immune systems involving cellular and humoral factors.
  • * Antimicrobial proteins and peptides play a vital role in combating bacterial and fungal infections.
  • * Understanding insect immunity offers insights into conserved defense mechanisms across species.

Related Experiment Videos