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An Automated Method to Perform The In Vitro Micronucleus Assay using Multispectral Imaging Flow Cytometry
Published on: May 13, 2019
Micronuclei-induction and its correlation to cell survival in HeLa cells treated with different doses of adriamycin
1Department of Radiobiology, Kasturba Medical College, Manipal, India.
Cancer Letters
|December 20, 1996
Abstract:
The treatment of HeLa cells with different concentrations of adriamycin (0, 5, 10, 25, 50 and 100 microg/ml) resulted in a significant and dose-dependent decline in the cell survival. Conversely, the frequency of micronuclei increased in a concentration-dependent manner. The micronuclei-induction and cell survival were found to be inversely related.
