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[Early auditory evoked potential. A diagnostic parameter in uremic encephalopathy]
1Klinik für Hals-Nasen-Ohren-Krankheiten und plastische Chirurgie, Klinikum Suhl.
HNO
|October 1, 1996
Summary
Chronic renal failure impacts brainstem auditory evoked responses (BAERs), showing prolonged latencies. Dialysis improves these auditory pathway functions, correlating with creatinine levels.
Area of Science:
- Neurology
- Nephrology
- Audiology
Context:
- Chronic renal failure (CRF) affects multiple organ systems, including the central nervous system.
- Auditory pathway function can be compromised in patients with CRF.
Purpose:
- To investigate the effects of chronic renal failure on brainstem auditory evoked responses (BAERs).
- To correlate BAER changes with serum creatinine levels, renal disease type, and dialysis.
- To track BAER alterations over a 3-year period.
Summary:
- BAERs in 87 CRF patients revealed altered wave morphology and prolonged latencies/interpeak intervals.
- Wave V latencies and I-V interpeak intervals correlated with serum creatinine.
- Dialysis demonstrated a positive effect, shortening wave latencies.
Impact:
- BAERs serve as a sensitive indicator of neurological dysfunction in CRF.
- Findings highlight the impact of uremia on auditory processing and the benefits of dialysis.
- Monitoring BAERs can document functional decline even in stable uremic conditions.