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[Pyonephrosis caused by torulosis glabrata]

J M Santa-Cruz1, C Marchal Escalona, D Pérez Rodríguez

  • 1Servicio de Urología del Hospital Universitario Virgen de la Victoria, Málaga.

Actas Urologicas Espanolas
|September 1, 1996
PubMed
Summary

Fungal urinary infections are rising, with Toruplosis glabrata causing 5-25% of cases. This study details a rare pyonephrosis case by Toruplosis glabrata, highlighting clinical presentation, diagnosis, and treatment strategies.

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Area of Science:

  • Urology
  • Mycology
  • Infectious Diseases

Background:

  • Fungal urinary tract infections (UTIs) are increasingly prevalent due to factors like broad-spectrum antibiotic use, rising immunocompromised populations, and longer lifespans of chronic patients.
  • Torulopsis glabrata (Candida glabrata) is the second most common fungal cause of UTIs, accounting for 5-25% of all fungal infections.
  • These infections pose a significant challenge in clinical settings, necessitating a better understanding of their epidemiology and management.

Observation:

  • A case of pyonephrosis, a severe kidney infection, caused by Torulopsis glabrata in a female patient is presented.
  • The patient's clinical presentation, diagnostic workup, and treatment course are described in detail.
  • This highlights the potential severity of Torulopsis glabrata UTIs.

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Findings:

  • The case illustrates a complex Torulopsis glabrata infection requiring aggressive management.
  • Successful treatment involved fluconazole therapy followed by nephrectomy.
  • This case underscores the importance of timely diagnosis and appropriate intervention for fungal pyonephrosis.

Implications:

  • This case report contributes to the understanding of Torulopsis glabrata pyonephrosis.
  • It emphasizes the need for vigilance in diagnosing and managing fungal UTIs, especially in at-risk populations.
  • Effective antifungal strategies and surgical interventions are crucial for favorable outcomes in severe cases.