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[Pyonephrosis caused by torulosis glabrata]
J M Santa-Cruz1, C Marchal Escalona, D Pérez Rodríguez
1Servicio de Urología del Hospital Universitario Virgen de la Victoria, Málaga.
Abstract:
Fungal urinary infections are becoming increasingly frequent as a result of widespread use of broad spectrum antibiotics, an increased number of immunocompromised patients and the greater longevity of chronic patients. Urinary tract infections by Toruplosis glabrata only come second in frequency after those caused by Candida albicans, accounting for 5 to 25% of all infections caused by fungi. The paper presents one case of pyonephrosis by Toruplosis glabrata in a female patient treated with fluconazole who later underwent nephrectomy. A description is made of the clinical picture, diagnosis and treatment of these infections.
Insights
Fungal urinary infections are rising, with Toruplosis glabrata causing 5-25% of cases. This study details a rare pyonephrosis case by Toruplosis glabrata, highlighting clinical presentation, diagnosis, and treatment strategies.
Area of Science:
- Urology
- Mycology
- Infectious Diseases
Background:
- Fungal urinary tract infections (UTIs) are increasingly prevalent due to factors like broad-spectrum antibiotic use, rising immunocompromised populations, and longer lifespans of chronic patients.
- Torulopsis glabrata (Candida glabrata) is the second most common fungal cause of UTIs, accounting for 5-25% of all fungal infections.
- These infections pose a significant challenge in clinical settings, necessitating a better understanding of their epidemiology and management.
Observation:
- A case of pyonephrosis, a severe kidney infection, caused by Torulopsis glabrata in a female patient is presented.
- The patient's clinical presentation, diagnostic workup, and treatment course are described in detail.
- This highlights the potential severity of Torulopsis glabrata UTIs.
Findings:
- The case illustrates a complex Torulopsis glabrata infection requiring aggressive management.
- Successful treatment involved fluconazole therapy followed by nephrectomy.
- This case underscores the importance of timely diagnosis and appropriate intervention for fungal pyonephrosis.
Implications:
- This case report contributes to the understanding of Torulopsis glabrata pyonephrosis.
- It emphasizes the need for vigilance in diagnosing and managing fungal UTIs, especially in at-risk populations.
- Effective antifungal strategies and surgical interventions are crucial for favorable outcomes in severe cases.