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Fractures in very low birth weight infants with rickets

E J Dabezies1, P D Warren

  • 1Orthopaedic Surgery Department, Texas Tech Health Sciences Center and University Medical Center, Lubbock 79415, USA.

Clinical Orthopaedics and Related Research
|February 1, 1997
PubMed

Insights

Very low birth weight infants can develop rickets and fractures. Risk factors include medical therapies and specific physical therapies, necessitating early recognition and appropriate treatment.

Area of Science:

  • Neonatalogy
  • Pediatric Orthopedics
  • Nutritional Science

Background:

  • Very low birth weight (VLBW) infants (<1500 g) are susceptible to nutritional deficiencies and complications.
  • Developmental rickets and fractures can significantly impact VLBW infants' long-term health and development.

Purpose of the Study:

  • To identify the incidence and characteristics of rickets and fractures in VLBW infants.
  • To determine risk factors associated with these conditions in VLBW infants.
  • To outline appropriate management strategies for VLBW infants diagnosed with rickets and fractures.

Main Methods:

  • A retrospective review of 247 VLBW infant cases over 42 months.
  • Diagnosis of rickets and fractures based on clinical and radiological findings.
  • Analysis of risk factors including medical history, therapies, and physical interventions.

Main Results:

  • Rickets diagnosed in 39% (96/247) of infants at a mean age of 50 days.
  • Fractures diagnosed in 10.5% (26/247) of infants at a mean age of 75 days.
  • A total of 98 fractures were observed in 26 infants, with ribs being the most common site.

Conclusions:

  • VLBW infants face a significant risk of developing rickets and fractures.
  • Hepatobiliary disease, total parenteral nutrition, diuretic therapy, and specific physical therapies are identified risk factors.
  • Early diagnosis and management with metabolic therapy and splinting are crucial for optimal outcomes.

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