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[Relations between stress in daily life and hypertensive cardiovascular accidents]

O Tochikubo1

  • 1Second Department of Internal Medicine, Urafune Hospital of Yokohama City University.

Rinsho Byori. the Japanese Journal of Clinical Pathology
|January 1, 1997
PubMed

Insights

Morning hours pose significant cardiovascular risks for hypertensive patients due to sudden increases in blood pressure and heart rate. These physiological changes, including decreased baroreceptor sensitivity, may reduce coronary blood flow during this critical period.

Area of Science:

  • Cardiology
  • Physiology
  • Hypertension Research

Context:

  • Patients with hypertension and cardiovascular disorders experience heightened stress during daily activities.
  • Cardiovascular events like heart attacks and strokes frequently occur in the morning hours.
  • Essential hypertension is characterized by specific hemodynamic alterations during the morning.

Purpose:

  • To investigate the hemodynamic factors contributing to the increased risk of cardiovascular events in the morning for hypertensive patients.
  • To understand the physiological mechanisms behind the morning surge in blood pressure and heart rate.
  • To explore the impact of these morning hemodynamic changes on coronary blood flow.

Summary:

  • Hypertensive individuals exhibit a morning surge in blood pressure, heart rate, and total peripheral resistance (TPR), alongside decreased baroreceptor sensitivity (BRS).
  • Factors contributing to this include decreased plasma volume, autonomic nervous system imbalance (increased LF/HF ratio), and a reduction in the BI index.
  • These collective hemodynamic shifts during morning hours may impair coronary blood flow, increasing cardiovascular risk.

Impact:

  • Highlights the critical nature of morning hours for hypertensive patients, suggesting a need for targeted monitoring and intervention.
  • Provides insights into the physiological basis of morning cardiovascular events, aiding in risk stratification.
  • Informs potential therapeutic strategies aimed at mitigating morning hemodynamic changes to improve cardiovascular outcomes.

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