Some additional results about polymorphisms in models of an additive quantitative trait under stabilizing selection
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Updated: Nov 2, 2026

Following the Dynamics of Structural Variants in Experimentally Evolved Populations
Published on: February 3, 2023
1Department of Ecology and Evolution, University of Chicago, IL 60637-1573, USA. sashu@pondside.uchicago.edu
Abstract:
The existence of two stable, symmetric (allelic frequency 0.5 in each locus) polymorphic states is demonstrated for a two-locus model of an additive quantitative trait under strong Gaussian selection. Linkage disequilibrium at one of the states is negative whereas it is positive at the other state. For a three-locus model, it is shown that in order to maintain a stable polymorphism in all three loci, selection must be sufficiently but not excessively strong relative to recombination. Also, positive linkage disequilibrium can be maintained in a three-locus model under stabilizing selection that is not very strong.
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