[Studies of changes in filtration angle after experimental administration of ethacrynic acid into the anterior chamber]

The aim of the study is to determine what charges occur in filtration angle after administration of ethacrynic acid solution into anterior chamber. The study was conducted in 9 rabbits. After administration of 0.5 mmol/l and 0.7 mmol/l epsilon. acid solution, oedema of cells, relaxation of structure of trabecular texture and cellular necrobiosis in filtration angle were detected. Intraocular pressure lowered by 6-7 mm Hg. It is possible that ethacrynic acid will be used as an agent inducing changes in filtration angle which reduce intraocular pressure.