[Experience with using high doses of cerebrolysin in vascular dementia]

The efficacy and tolerability of high-dose neurotrophic drug cerebrolysin was studied in 20 patients with vascular dementia diagnosed by criteria NINDS-AIREN and DSM-IV. The drug was well tolerated, affected positively cognitive function, especially neurodynamic processes. EEG featured after treatment intensification of rapid rhythms power and a decrease in delta-activity spectrum. The highest effect of cerebrolysin was achieved in patients with mild cognitive defects.