[Localization of epileptogenic foci and visualization of propagating process in the seizure discharges using...

Electrocorticogram (ECoG) of intractable focal epilepsy was analyzed using AR model, wavelet analysis and crosscorrelation analysis. The sequential 3-dimensional visualization technique of phase shift maps was developed to localize the epileptic foci and to study their propagation process. The crosscorrelation of the epileptic discharges was calculated between the electrodes in every unit of time, to get the phase shift. More than two epileptogenic foci were localized and two kinds of propagating process were shown. These findings suggest that two kinds of mechanism might work in development of epileptic discharges, and our newly developed visualization technique is useful to investigate the epileptogenesis etiology.