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Stool and urinary sugars in normal neonates

R Counahan, J Walker-Smith

Archives of Disease in Childhood

|July 1, 1976

Summary

This summary is machine-generated.

In healthy newborns, low stool pH and the presence of reducing substances may indicate lactose malabsorption. Further testing is recommended for accurate diagnosis in neonates.

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Area of Science:

Neonatal physiology
Gastroenterology
Pediatric nutrition

Background:

Neonatal stool characteristics can offer insights into digestive health.
Understanding normal ranges is crucial for identifying potential issues in newborns.

Purpose of the Study:

To investigate stool pH and reducing substances in healthy neonates.
To identify patterns indicative of carbohydrate malabsorption in infants.

Main Methods:

Analysis of stool pH and reducing substances in 51 neonates (5-8 days old).
Stool chromatography performed on select infants to identify specific sugars.
Urine chromatography conducted on 60 neonates to detect sugar levels.

Main Results:

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Six neonates had a stool pH of 5 or less; 4 were exclusively breastfed.
Reducing substances (0-5% or more) were detected in 16 stools.
Stool chromatography revealed lactose malabsorption patterns in 13 infants; 3 had oligosaccharides or maltose.
Detectable sugars in urine were found in 11 neonates, with 3 exceeding 50 mg/100 ml.

Conclusions:

Low stool pH and reducing substances may suggest carbohydrate malabsorption in neonates.
Lactose malabsorption is a potential finding in normal-appearing newborns.
Further investigation of neonatal digestive function is warranted.