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Upper urinary tract stones & Ureaplasma urealyticum
1Department of Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh.
The Indian Journal of Medical Research
|January 1, 1997
Summary
Infection stones are uncommon in nephrolithiasis patients, with most stones being calcium oxalate phosphate. Removal of renal stones is crucial for treating fastidious organisms like Ureaplasma urealyticum.
Area of Science:
- Nephrology
- Microbiology
- Biochemistry
Background:
- Nephrolithiasis (kidney stones) can be associated with bacterial infections.
- Understanding the microbial composition of kidney stones is crucial for effective treatment.
Purpose of the Study:
- To investigate the prevalence of bacterial and Ureaplasma urealyticum infections in kidney stones.
- To analyze the biochemical composition of kidney stones and correlate it with microbial findings.
Main Methods:
- Culture of renal stones and pelvic urine from 70 nephrolithiasis patients.
- Biochemical analysis and scanning electron microscopy of stones.
- Isolation and identification of micro-organisms.
Main Results:
- Micro-organisms were isolated from 47% of renal stones.
- Urea-splitting bacteria, including Ureaplasma urealyticum, were identified.
- Pelvic urine accurately reflected stone bacteriology, unlike voided urine.
- Most stones were calcium oxalate phosphate (79%), with none of struvite composition.
- Infection stones were found to be uncommon.
Conclusions:
- Infection stones appear uncommon in this region.
- The presence of fastidious organisms like Ureaplasma urealyticum and multi-drug resistant bacteria in renal stones necessitates surgical removal for complete cure.