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Increased anion gap after liver transplantation
1Division of Nephrology, Medical College of Virginia, Virginia Commonwealth University, Richmond 23298-0160, USA.
The American Journal of the Medical Sciences
|February 1, 1997
Summary
Massive fibrinolysis in liver transplant patients led to renal failure and required fresh frozen plasma. This treatment increased plasma proteins, causing a correlated rise in the anion gap, suggesting hyperproteinemic acidosis.
Area of Science:
- Nephrology
- Transplant Surgery
- Hematology
Background:
- Massive fibrinolysis following liver transplantation can lead to acute kidney injury.
- Treatment often involves large volumes of fresh frozen plasma (FFP), increasing plasma protein levels.