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Defining Substrate Specificities for Lipase and Phospholipase Candidates
Published on: November 23, 2016
Inhibition of pancreatic lipase by phenolic acids--examination in vitro
1Division of Food Science, Polish Academy of Sciences, Olsztyn, Poland.
Abstract:
The influence of addition 2,4,6,8, and 10 microM of benzoic and cinnamic acids and selected phenolic acids (salicylic, p-hydroxybenzoic, gentisic, protocatechuic, vanillic, syringic, o-coumaric, p-coumaric, caffeic, ferulic, sinapic) on the activity of pancreatic lipase was examined in vitro. The strongest inhibition activities were observed with caffeic, ferulic and benzoic acid, while sinapic and gentisic acids produced the lowest inhibition.
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