Related Experiment Video
Updated: Aug 11, 2026

Analyzing and Building Nucleic Acid Structures with 3DNA
Published on: April 26, 2013
A good turn for DNA: the structure of integration host factor bound to DNA
1Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, USA. tome@jeckle.med.harvard.edu
Abstract:
The crystal structure of integration host factor (IHF) complexed with DNA shows how a small heterodimeric protein can induce a big bend in DNA. IHF exerts leverage in the minor groove and wraps DNA around the body of the protein, providing another example of sequence-specific recognition of the minor groove.
More Related Videos
09:31Amplification, Next-generation Sequencing, and Genomic DNA Mapping of Retroviral Integration Sites
Published on: March 22, 2016
12:19Tools to Study the Role of Architectural Protein HMGB1 in the Processing of Helix Distorting, Site-specific DNA Interstrand Crosslinks
Published on: November 10, 2016
Related Concept Videos
The DNA Helix
The DNA Helix
The DNA Replication Fork
Single-Strand DNA Binding Proteins
The DNA Helix
The DNA Replication Fork