Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Serum cholesterol and chronic hepatitis C

G Maggi1, R Bottelli, D Gola

  • 1Divisione Medica Ospedale FBF, Erba, Italy.

The Italian Journal of Gastroenterology
|October 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Incidence of pemphigoid diseases in Northern Germany in 2016 - first data from the Schleswig-Holstein Registry of Autoimmune Bullous Diseases.

Journal of the European Academy of Dermatology and Venereology : JEADV·2021
Same author

Letter: Sorafenib hepatotoxicity may be enhanced during treatment of advanced hepatocellular carcinoma in HIV-infected patients.

Alimentary pharmacology & therapeutics·2013
Same author

Search for signatures of extra dimensions in the diphoton mass spectrum at the large hadron collider.

Physical review letters·2012
Same author

[Anaesthetic implications of Gorham syndrome].

Revista espanola de anestesiologia y reanimacion·2012
Same author

Search for a vectorlike quark with charge 2/3 in t+Z events from pp collisions at √s=7 TeV.

Physical review letters·2012
Same author

Search for B(s)(0) → μ+ μ- and B(0) → μ+ μ- decays in pp collisions at sqrt[s] = 7 TeV.

Physical review letters·2011

Serum cholesterol levels are significantly lower in patients with chronic Hepatitis C compared to Hepatitis B. Viral hepatitis type was the sole independent factor influencing cholesterol levels in this study.

Area of Science:

  • Hepatology
  • Biochemistry
  • Viral Hepatitis Research

Background:

  • Chronic hepatitis B and C are prevalent liver diseases.
  • Serum lipid profiles, particularly cholesterol, can be altered in chronic liver disease.
  • Understanding these alterations is crucial for patient management.

Purpose of the Study:

  • To compare total serum cholesterol levels between patients with chronic hepatitis B and chronic hepatitis C.
  • To identify factors associated with serum cholesterol levels in these patient groups.
  • To investigate the independent relationship between viral hepatitis type and serum cholesterol.

Main Methods:

  • Cross-sectional study involving 100 patients each with chronic hepatitis B and C (without cirrhosis).
  • Comparison of mean serum cholesterol levels with age- and sex-matched control groups.

Related Experiment Videos

  • Analysis of cholesterol levels in relation to various clinical and laboratory parameters including liver function, disease duration, alcohol intake, BMI, liver enzymes, steatosis, and histological activity index.
  • Multivariate regression analysis to determine independent predictors of serum cholesterol.

    • Main Results:

    • Mean serum cholesterol was significantly lower in Hepatitis C patients (176 mg/dl) than in Hepatitis B patients (194 mg/dl) and controls (198 mg/dl).
    • A higher percentage of Hepatitis C patients had low serum cholesterol (< 150 mg/dl) compared to Hepatitis B patients (28% vs 10%).
    • Multivariate analysis confirmed that the type of viral infection was the only independent factor related to serum cholesterol levels.

    Conclusions:

    • Chronic Hepatitis C is independently associated with lower serum cholesterol levels compared to chronic Hepatitis B.
    • Serum cholesterol levels may serve as a potential biomarker or indicator in differentiating between chronic hepatitis B and C.
    • Further research is warranted to explore the clinical implications of these findings.