Related Experiment Videos
[Severe surgical infection with no information in terms of bacteria]
H Tanimura1, T Tsunoda, K Ishimoto
1Second Department of Surgery, Wakayama Medical School, Japan.
Abstract:
The incidence of bacteria caused postoperative infections was performed at the timing when bacteria or fungi is not yet detected. This period is important for management of postoperative infections. MRSA, E. faecalis, P. aeruginosa and fungi were detected with high frequency irrespective of the surgical area. After the operation of esophageal cancer, the most frequent infection was postoperative pneumonia, and the isolated bacteria was P. aeruginosa frequently. In the cases of gastric cancer, hepato-biliary-pancreas cancer and colorectal cancer, intraabdominal sepsis was the highest incidence, and the isolated bacteria was E. faecalis. In terms of intravenous catheter infection, fungus was common. Thus, it may suggest that we can identify the bacteria caused, and the management for postoperative infections was performed appropriately by using the antibiotics which have the sensitive against the expected pathogen.
Insights
This study identified common pathogens causing postoperative infections, including Methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa. Understanding these bacteria aids in selecting appropriate antibiotic treatments for better patient outcomes.
Area of Science:
- Infectious Diseases
- Surgical Site Infections
- Microbiology
Background:
- Postoperative infections pose a significant threat to patient recovery.
- Early detection and management of causative pathogens are crucial for effective treatment.
- Commonly isolated microorganisms include Methicillin-resistant Staphylococcus aureus (MRSA), Enterococcus faecalis, Pseudomonas aeruginosa, and fungi.
Purpose of the Study:
- To investigate the incidence and types of bacterial and fungal pathogens causing postoperative infections.
- To correlate specific pathogens with different types of cancer surgeries and intravenous catheter infections.
- To inform targeted antibiotic strategies for managing postoperative infections.
Main Methods:
- Prospective surveillance of postoperative infections.
- Microbiological culture and identification of bacteria and fungi.
- Analysis of infection incidence based on surgical site and type of cancer (esophageal, gastric, hepato-biliary-pancreatic, colorectal).
Main Results:
- High frequency of MRSA, E. faecalis, P. aeruginosa, and fungi detected across various surgical areas.
- Postoperative pneumonia was most common after esophageal cancer surgery, with P. aeruginosa as a frequent isolate.
- Intraabdominal sepsis was most common in gastric, hepato-biliary-pancreatic, and colorectal cancer surgeries, with E. faecalis as a frequent isolate.
- Fungal infections were common in intravenous catheter-associated infections.
Conclusions:
- Specific pathogens are frequently associated with different types of cancer surgeries and complications.
- Identifying common pathogens allows for the selection of antibiotics with known sensitivity profiles.
- This approach can lead to more appropriate and effective management of postoperative infections.