Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Retinal hemodynamics in middle-aged normal subjects

A Yoshida1, G T Feke, H Ogasawara

  • 1Department of Ophthalmology, Asakihawa Medical College, Japan.

Ophthalmic Research
|January 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

HPC-1 is associated with synaptotagmin and omega-conotoxin receptor.

The Journal of biological chemistry·1992
Same author

[The first cholera case diagnosed early in the clinical laboratory by DNA probe method].

Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases·1992
Same author

Parathyroid hormone inhibits immunoglobulin production without affecting cell growth in human B cells.

Clinical immunology and immunopathology·1992
Same author

Structural differences between heparan sulphates of proteoglycan involved in the formation of basement membranes in vivo by Lewis-lung-carcinoma-derived cloned cells with different metastatic potentials.

The Biochemical journal·1992
Same author

The quality and quantity of dietary protein affect brain protein synthesis in rats.

The Journal of nutrition·1992
Same author

Evaluation of thyroid function in patients with isolated adrenocorticotropin deficiency.

The American journal of the medical sciences·1992

Middle-aged adults maintain similar retinal blood flow to younger adults despite higher blood pressure. This suggests increased vascular resistance or effective autoregulation in aging eyes.

Area of Science:

  • Ophthalmology
  • Physiology
  • Gerontology

Background:

  • Aging impacts ocular hemodynamics and vascular function.
  • Understanding retinal blood flow changes with age is crucial for eye health.

Purpose of the Study:

  • To compare retinal blood flow and perfusion pressure between middle-aged and younger healthy adults.
  • To investigate age-related changes in retinal vascular resistance and autoregulation.

Main Methods:

  • Laser Doppler technique and monochromatic photography for retinal blood flow measurement.
  • Systemic blood pressure and intraocular pressure monitoring.
  • Calculation of retinal perfusion pressure.

Main Results:

  • Total retinal blood flow was comparable between middle-aged (73 ± 13 µL/min) and younger (80 ± 12 µL/min) subjects.

Related Experiment Videos

  • Retinal perfusion pressure was significantly higher in older subjects due to elevated systemic blood pressure.
  • Increased vascular resistance was inferred in older subjects despite similar flow rates.

    • Conclusions:

    • Middle-aged individuals exhibit maintained total retinal blood flow despite elevated perfusion pressure.
    • This finding may indicate an aging-related increase in vascular resistance or efficient retinal autoregulation.
    • Further research is needed to differentiate between aging phenomena and autoregulatory capacity.