Recurrence of endogenous cortisol secretion after bilateral total adrenalectomy--2 cases

Bilateral total adrenalectomy is a common treatment for Cushing's Syndrome in underdeveloped countries where limited resources restrict the use of extensive investigations, where the source of ACTH secretion is not identified or where neurosurgical facilities are minimal. Two cases of recurrence of cortisol secretion managed at the University Hospital of the West Indies are presented. The aetiology is discussed.