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Updated: Aug 10, 2026
In vitro Assessment of Myocardial Protection following Hypothermia-Preconditioning in a Human Cardiac Myocytes Model
Published on: October 27, 2020
Complex thoracic vascular injury repair using deep hypothermia and circulatory arrest
1Department of Cardiothoracic Surgery, University of Cape Town, South Africa.
Insights
A stab wound caused severe injuries to major aortic arch arteries and veins, including a fistula. Successful surgical repair utilized cardiopulmonary bypass with deep hypothermia and circulatory arrest.
Area of Science:
- Vascular Surgery
- Trauma Management
- Cardiopulmonary Bypass
Background:
- Penetrating trauma to the aortic arch presents significant surgical challenges.
- Injuries to the innominate, common carotid, and subclavian arteries require immediate and effective intervention.
- Iatrogenic or traumatic arteriovenous fistulas complicate vascular repair.
Abstract:
A 61-year-old man with a penetrating injury to the innominate artery, left common carotid artery, and left subclavian artery at their origins from the aortic arch with associated injuries to both innominate veins and an innominate artery to vein fistula after a single stab wound is described. The patient was managed successfully using cardiopulmonary bypass together with deep hypothermia and circulatory arrest. Presentation and management are discussed.
