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Acquired von Willebrand's disease: a concise review
M R Rinder1, R E Richard, H M Rinder
1Department of Medicine, University of Maryland Medical Center, Baltimore, USA.
American Journal of Hematology
|February 1, 1997
Summary
Acquired von Willebrand's disease (AvWD) in adults is often linked to lymphoproliferative disorders. Intravenous immunoglobulin shows promise for treating AvWD by clearing antibody-von Willebrand factor complexes.
Area of Science:
- Hematology
- Immunology
- Internal Medicine
Background:
- Acquired von Willebrand's disease (AvWD) is an adult-onset bleeding disorder.
- AvWD is frequently associated with lymphoproliferative diseases, monoclonal gammopathies, malignancies, autoimmune conditions, hypothyroidism, and certain drugs.
- A case of AvWD with monoclonal gammopathy requiring cardiac surgery is presented.