Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The gene encoding bovine brain-derived neurotrophic factor (BDNF)

S F Arab1, K Krohn, A Lachmund

  • 1Department of Anatomy and Cell Biology (Neuroanatomy), University of Heidelberg, Germany.

Gene
|January 31, 1997
PubMed
Summary

Researchers detailed the nucleotide sequence for bovine brain-derived neurotrophic factor (BDNF) cDNA. This sequence was then compared with BDNF genes from other species to understand evolutionary relationships.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Bone quality relies on hyaluronan synthesis - Insights from mice with complete knockout of hyaluronan synthase expression.

Matrix biology plus·2024
Same author

Lessons learned with Bone Health TeleECHO: making treatment decisions when guidelines conflict.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2019
Same author

Images from the surface of asteroid Ryugu show rocks similar to carbonaceous chondrite meteorites.

Science (New York, N.Y.)·2019
Same author

Examining the treatment gap and risk of subsequent fractures among females with a fragility fracture in the US Medicare population.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2017
Same author

Different in vivo and in vitro transformation of intestinal stem cells in mismatch repair deficiency.

Oncogene·2016
Same author

Novel genes on rat chromosome 10 are linked to body fat mass, preadipocyte number and adipocyte size.

International journal of obesity (2005)·2016

Area of Science:

  • Molecular Biology
  • Genetics
  • Neuroscience

Background:

  • Brain-derived neurotrophic factor (BDNF) is crucial for neuronal survival, growth, and function.
  • Understanding BDNF gene sequences across species aids in comparative genomics and evolutionary studies.

Purpose of the Study:

  • To determine and present the nucleotide (nt) sequence of the cDNA encoding bovine BDNF.
  • To compare the bovine BDNF nt and peptide sequences with those from other species.

Main Methods:

  • cDNA sequencing to obtain the nucleotide sequence of bovine BDNF.
  • Bioinformatic analysis for sequence comparison and alignment.

Main Results:

  • The complete nucleotide sequence for bovine BDNF cDNA was elucidated.

Related Experiment Videos

  • Comparative analysis revealed similarities and differences between bovine BDNF and homologous sequences from other species.

    • Conclusions:

    • The determined bovine BDNF sequence provides a valuable resource for further research.
    • Cross-species comparisons contribute to understanding BDNF evolution and functional conservation.