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Tourette's syndrome in the year 2000
1Department of Psychiatry and Behavioural Sciences, University College London, Medical School, Middlesex Hospital, United Kingdom.
The Australian and New Zealand Journal of Psychiatry
|December 1, 1996
Summary
Research on Tourette's syndrome (TS) has shifted from psychological to neurobiological perspectives, with significant advances expected in genetics and neuroimaging. Increased awareness will likely lead to more diagnoses, presenting new challenges for healthcare and education.
Area of Science:
- Neurology
- Genetics
- Psychiatry
Background:
- Tourette's syndrome (TS) research has evolved significantly over time.
- Early research focused on psychological aspects, while modern studies emphasize neurobiology.
Purpose of the Study:
- To review the current state of knowledge regarding Tourette's syndrome.
- To identify key research areas poised for advancement in the 21st century.
Main Methods:
- A chronological literature review using Index Medicus and MEDLINE databases from 1885 to the present.
- Examination of research trends, focusing on the shift from psychological to neurobiological viewpoints.
- Analysis of parallels with Huntington's Disease and Parkinson's Disease research for future TS directions.
Main Results:
- A substantial increase in TS literature volume since 1885, with accelerated growth post-1980.
- Current research focuses on genetics, comorbid conditions, neuroimaging, treatments, epidemiology, and education.
- Insights from Huntington's Disease and Parkinson's Disease research highlight potential in predictive testing, gene therapy, and neural transplants for TS.
Conclusions:
- Significant advancements in TS genetics and neuroimaging are anticipated around the year 2000.
- New therapeutic developments for Tourette's syndrome are expected.
- Increased awareness among healthcare professionals and educators is likely to raise diagnosis rates, necessitating enhanced health and educational resources.