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Updated: Aug 10, 2026

A Murine Model of Irreversible and Reversible Unilateral Ureteric Obstruction
Published on: December 20, 2014
Ureteroceles in children: an ongoing challenge
1Department of Paediatric Surgery, Westmead Centre, Sydney, NSW, Australia.
Insights
Individualized treatment for pediatric ureteroceles is crucial. Antenatal diagnosis enables organized postnatal care, including antibiotic prophylaxis and investigations to assess urinary tract function and anatomy.
Area of Science:
- Pediatric Urology
- Diagnostic Imaging
- Surgical Management
Background:
- Ureteroceles in children necessitate a personalized treatment strategy.
- Antenatal diagnosis is optimal for timely postnatal management and investigations.
- Postnatal assessment must evaluate both upper and lower urinary tracts.
Purpose of the Study:
- To outline an individualized approach to the diagnosis and management of ureteroceles in children.
- To detail appropriate investigations for assessing upper and lower urinary tract status.
- To describe surgical principles for optimal patient outcomes.
Main Methods:
- Renal and bladder ultrasound and micturating cystourethrography for reflux and obstruction detection.
- Technetium Tc99m dimercaptosuccinic acid renal scan for evaluating renal function, especially upper moiety.
- Tc99m-mercaptoacetyltriglycine isotope scan with volume expansion and furosemide diuresis for quantitating function and obstruction.
- Intravenous urography for detailed anatomic information in functional upper moieties.
Main Results:
- Antenatal diagnosis facilitates organized postnatal urinary antibiotic prophylaxis and investigations.
- Ultrasound and micturating cystourethrography identify vesicoureteric reflux and bladder outlet obstruction.
- Renal scans effectively evaluate upper moiety function and overall renal function.
- Combined functional and obstruction assessment is achievable with specific isotope scans and diuresis.
Conclusions:
- An individualized, tailored approach is essential for managing pediatric ureteroceles.
- Restoration of near-normal anatomy and preservation of functional renal tissue are key surgical principles.
- Comprehensive postnatal investigations guide appropriate management strategies for optimal renal preservation.
Abstract:
The treatment of ureteroceles in children requires an individualised approach. Antenatal diagnosis is the ideal, so that postnatal urinary antibiotic prophylaxis and appropriate investigations can be organised. Postnatal investigations should assess both upper and lower urinary tract. Renal and bladder ultrasound and radiographic micturating cystourethragraphy under antibiotic cover will both detect vesicoureteric reflux and assess any bladder outlet obstruction due to the ureterocele. Renal function, particularly of the upper moiety, is best evaluated by technetium Tc99m dimercaptosuccinic acid renal scan. Both function and obstruction can be quantitated by the Tc99m-mercaptoacetyltriglycine isotope scan with intravenous volume expansion (10 ml/kg) and furosemide diuresis (1 mg/kg). Intravenous urography provides the best anatomic information when the upper moiety is functional. The surgical management is based on the clinical situation, which is often variable, and therefore needs to be tailored for each patient. The general principles include restoration of anatomy to as near normal as possible and preservation of functional renal tissue.
Related Concept Videos
Ureters
Urinary Tract Calculi I: Introduction
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
Urinary Tract Calculi III: Medical Management
Urinary Tract Calculi V: Nursing Management
Urinary Tract Calculi VI: Surgical Management

