[Atrial septal defect percutaneous transvenous occlusion with the buttoned device]

Area of Science:

• Cardiology
• Interventional Cardiology
• Medical Devices

Background:

• Atrial septal defects (ASDs) are congenital heart conditions requiring intervention.
• Percutaneous transvenous occlusion offers a less invasive alternative to surgical repair.
• Evaluating novel devices for ASD closure is crucial for improving patient care.

Purpose of the Study:

• To assess the clinical experience and outcomes of using the Sideris device for percutaneous transvenous occlusion of atrial septal defects (ASDs).

Main Methods:

• A total of 36 ASD occlusion procedures were performed in 32 patients (27 female, 5 male; mean age 16 years).
• Patients had secundum ASDs with clinical and hemodynamic compromise, with specific size criteria met.
• Both the basic and self-centered Sideris device models were used, employing direct implant or over-the-wire techniques.

Main Results:

• Successful occlusion was achieved in 90.63% of patients (29/32).
• Three patients required surgical removal of the device due to inadequate position or embolization, with no associated morbidity or mortality.
• Trivial residual shunts were observed in 9.4% immediately post-procedure, decreasing to 4.5% at 12-month follow-up.

Conclusions:

• The Sideris device demonstrates safety and efficiency for ASD occlusion in appropriately selected patients.
• Initial residual shunts are common but tend to resolve, not hindering clinical or hemodynamic improvement.
• The Sideris device represents a viable option for percutaneous ASD closure.