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Updated: Aug 4, 2026
04:41
Measuring Lactase Enzymatic Activity in the Teaching Lab
Published on: August 6, 2018
[Use of enzyme substitutes in hypolactasia]
L N Valenkevich1, O I Iakhontova, M E Shubina
1Department of Propaedeutics of Internal Diseases, University, Petrozavodsk.
Klinicheskaia Meditsina
|January 1, 1996
Summary
Lactrase, a lactase drug, effectively treats hypolactasia by aiding lactose digestion. Clinical studies show it compensates for reduced natural lactase production, improving symptoms in most patients.
Area of Science:
- Biochemistry
- Gastroenterology
- Pharmacology
Context:
- Lactose intolerance, or hypolactasia, affects individuals with insufficient endogenous lactase.
- Clinical symptoms manifest after lactose consumption, impacting quality of life.
Purpose:
- To evaluate the efficacy of lactrase, a lactase enzyme preparation.
- To assess lactrase's ability to compensate for decreased endogenous lactase production in hypolactasia patients.
Summary:
- Clinical and laboratory studies were conducted on 28 patients with hypolactasia.
- Administration of 250 mg or 500 mg of lactrase with lactose significantly improved clinical symptoms.
- Lactrase demonstrated a reliable effect on glycemia and galactose levels post-lactose challenge.
Impact:
- Lactrase is a highly effective therapeutic agent for managing hypolactasia.
- The drug aids in the clinical compensation of lactase deficiency.
- Results support lactrase as a valuable treatment option for lactose maldigestion.
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