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[Nervous system lesions in patients with ixodid tick-borne borreliosis]

N N Vorob'eva, A Ia Burylov, G M Volegova

    Meditsinskaia Parazitologiia I Parazitarnye Bolezni
    |July 1, 1996
    PubMed

    Insights

    Ixodes tick-borne borreliosis (ITBB) in Russia

    Area of Science:

    • Medical Microbiology
    • Neurology
    • Epidemiology

    Context:

    • The Perm Region in Russia is endemic for Ixodes tick-borne borreliosis (ITBB).
    • Previous etiological studies identified Borrelia garinii and Borrelia afzelii as the primary causative agents.
    • ITBB commonly presents with neurological and dermatological symptoms.

    Purpose:

    • To investigate the clinical manifestations and neurological involvement in patients with Ixodes tick-borne borreliosis (ITBB) in the Perm Region.
    • To correlate clinical findings with etiological data and compare ITBB presentation in Russia with Western Europe.

    Summary:

    • A study of 646 patients with ITBB in the Perm Region (1990-1994) revealed central and peripheral nervous system involvement at all disease stages.
    • Prevalent neurological manifestations included encephalitis, encephalomyeloradiculoneuropathies, and neuropathies, particularly in patients without erythema migrans.
    • The spectrum and incidence of neurological syndromes in Russian ITBB cases resemble those observed in Western Europe.

    Impact:

    • Highlights the significant neurological burden of ITBB in the Perm Region.
    • Underscores the importance of recognizing diverse neurological presentations, especially in erythema migrans-negative cases.
    • Provides valuable epidemiological and clinical data for understanding and managing ITBB in Russia and potentially other regions.

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