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Longitudinal studies of blood pressure in children
1School of Public Health, Beijing Medical University, People's Republic of China.
Insights
This six-year study in China found that children's blood pressure generally increases with age. While blood pressure tracking in children shows weak to moderate correlation, it increases with age, suggesting limited long-term prediction.
Area of Science:
- Pediatrics
- Cardiovascular Health
- Public Health
Background:
- Childhood blood pressure tracking is crucial for predicting adult hypertension.
- Understanding longitudinal blood pressure changes in children is essential for early intervention.
- Previous research on blood pressure tracking in Chinese children is limited.
Purpose of the Study:
- To investigate longitudinal changes in blood pressure among Chinese children.
- To assess the
- tracking phenomenon
- of blood pressure in a pediatric cohort.
- To identify factors associated with blood pressure levels in children.
Main Methods:
- A six-year longitudinal study involving 2,946 children (aged 4-14 years) in Beijing, China.
- Initial blood pressure measurements in 1981, with follow-up measurements in 1985 and 1987.
- Statistical analysis including tracking coefficients and multiple stepwise regression.
Main Results:
- Average blood pressure levels increased with age, even after adjusting for height and weight.
- Systolic blood pressure tracking coefficients showed weak to moderate levels, increasing with age.
- Only 30% of children in the highest systolic blood pressure percentile maintained their status after four years.
- Systolic blood pressure correlated with body weight, pulse rate, serum glucose, and HDL-C.
- Diastolic blood pressure correlated with pulse rate and serum glucose.
Conclusions:
- Childhood blood pressure shows an increasing trend with age in the studied Chinese cohort.
- The
- tracking phenomenon
- of blood pressure in children is present but shows limited predictability over extended periods.
- Body weight, pulse rate, serum glucose, and HDL-C are significant correlates of systolic blood pressure in children.
- Pulse rate and serum glucose are key correlates of diastolic blood pressure in children.
Abstract:
A longitudinal study of six years was conducted to find out the pattern of longitudinal changes of blood pressure and to affirm the "tracking phenomenon" of blood pressure in children in China. We initially measured blood pressure and related parameters of 2,946 children (aged 4-14 years) in 1981 at Fanshan county, Beijing, and then two follow-up remeasurements were conducted in 1985 and 1987, respectively. The results indicated that: the average level of blood pressure increases with age even after adjusting for height and weight; tracking coefficients of systolic blood pressure range from weak to moderate levels, increasing with age. Only 30% of the children whose systolic blood pressure was beyond the 90th percentile of the systolic pressure distribution at the first examination remained at the same region after four years. Multiple stepwise regression was used to determine factors correlated with blood pressure. Our results indicate that systolic blood pressure in children is correlated with body weight, pulse rate, serum glucose and HDL-C, while diastolic blood pressure is correlated only with pulse rate and serum glucose.
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