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Longterm effects of endoscopic sphincterotomy on gall bladder motility
1First Department of Surgery, Kyorin University School of Medicine, Tokyo, Japan.
Gut
|December 1, 1996
Summary
Endoscopic sphincterotomy improves gallbladder motility long-term, reducing fasting volume and increasing contraction. This may lower risks of cholecystitis and gallstones after the procedure.
Area of Science:
- Gastroenterology
- Biliary System Physiology
- Endoscopic Procedures
Background:
- Endoscopic sphincterotomy (ES) can lead to acute cholecystitis or gallstone formation in patients with intact gallbladders.
- ES may negatively impact gallbladder motility.
Purpose of the Study:
- To prospectively assess the long-term effects of ES on gallbladder motility.
- Evaluate changes in gallbladder function post-ES.
Main Methods:
- Prospective study of 32 patients with intact gallbladders undergoing ES for choledocholithiasis.
- Gallbladder function assessed via ultrasonography (fasting volume, post-caerulein contraction) before and up to 5 years after ES.
Main Results:
- ES resulted in a patent, enlarged orifice throughout the 5-year follow-up.
- Gallbladder fasting volume decreased, and maximum contraction increased significantly post-ES (p < 0.05) compared to pre-ES values.
- These functional improvements occurred irrespective of pre-existing gallstones.
Conclusions:
- ES induces long-term positive changes in gallbladder motility, decreasing fasting volume and enhancing contraction.
- These functional improvements following ES may reduce the risk of developing acute cholecystitis or gallstones.
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