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Related Experiment Videos

Therapeutic renal infarction

P W Bergreen, J Woodside, S B Paster

    The Journal of Urology
    |September 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Therapeutic renal infarction using gelfoam before nephrectomy aided surgery for hypernephroma patients. While effective, it caused post-infarction syndrome, and one patient experienced limb gangrene due to embolization.

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    Area of Science:

    • Interventional Radiology
    • Nephrology
    • Oncology

    Background:

    • Hypernephroma (renal cell carcinoma) often requires nephrectomy.
    • Pre-operative strategies aim to reduce surgical complications like blood loss.
    • Renal infarction is a potential therapeutic intervention.

    Purpose of the Study:

    • To evaluate the efficacy and safety of pre-nephrectomy therapeutic renal infarction using gelfoam in hypernephroma patients.
    • To assess the impact of this technique on surgical facilitation and blood loss.
    • To document post-infarction complications and outcomes, including effects on blood pressure control in dialysis patients.

    Main Methods:

    • Ten patients with hypernephroma underwent therapeutic renal infarction via gelfoam injection into the renal artery.

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  • One dialysis patient received bilateral renal infarction.
  • Outcomes including surgical facilitation, blood loss, post-infarction syndrome, and complications were monitored.

    • Main Results:

    • Renal infarction facilitated nephrectomy and decreased blood loss in hypernephroma patients.
    • Most patients experienced post-infarction syndrome (flank pain, fever, nausea).
    • A dialysis patient showed improved blood pressure control after bilateral infarction, but suffered distal gelfoam embolization leading to foot gangrene.

    Conclusions:

    • Pre-nephrectomy renal infarction with gelfoam is a viable technique for hypernephroma, aiding surgery and reducing blood loss.
    • Post-infarction syndrome is a common complication.
    • Careful embolization technique is crucial to prevent serious complications like distal embolization and gangrene.