Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Prostatic involvement by transitional cell carcinoma: pathogenesis, patterns and prognosis

P F Schellhammer, M A Bean, W F Whitmore

    The Journal of Urology
    |September 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    What is the available evidence to support immediate adjuvant intravesical chemotherapy after transurethral resection of superficial transitional cell carcinoma of the bladder?

    Urologic oncology·2011
    Same author

    Intravesical chemotherapy and immunotherapy for superficial tumors Basic mechanism of action and future direction.

    Urologic oncology·2011
    Same author

    Expression of prostate-specific membrane antigen in normal, benign, and malignant prostate tissues.

    Urologic oncology·2011
    Same author

    PSA response to secondary androgen deprivation following failed treatment of metastatic prostate cancer with the antiandrogen casodex.

    Urologic oncology·2011
    Same author

    Overview of contents.

    Urologic oncology·2011
    Same author

    Randomized intergroup comparison of bacillus calmette-guerin immunotherapy and mitomycin C chemotherapy prophylaxis in superficial transitional cell carcinoma of the bladder a southwest oncology group study.

    Urologic oncology·2011
    Same journal

    On the Memoryless Property in Markov Models for NMIBC Cost-Effectiveness Analysis.

    The Journal of urology·2026
    Same journal

    Multi-institutional Assessment of Performance Metrics for MRI-targeted Transperineal Prostate Biopsy.

    The Journal of urology·2026
    Same journal

    Urinary Supersaturation in a Randomized Trial among Individuals with Recurrent Nephrolithiasis comparing Empiric versus Selective Preventive Therapy: The URINE Trial.

    The Journal of urology·2026
    Same journal

    The FDA Should Allow More BCG Strains into the US Market: How Recent Landmark Trials Expose a Regulatory Paradox.

    The Journal of urology·2026
    Same journal

    Let's Shift the Focus from Death to Life after Fournier's Gangrene.

    The Journal of urology·2026
    Same journal

    Endourology and Nephrolithiasis.

    The Journal of urology·2026
    See all related articles

    Transitional cell carcinoma of the bladder can invade the prostate via ductal or stromal patterns. Stromal invasion significantly lowers survival, but combined treatment offers a 20% 5-year survival rate.

    Area of Science:

    • Uro-oncology
    • Pathology

    Background:

    • Prostatic involvement by bladder transitional cell carcinoma presents diverse histologic patterns.
    • These patterns range from ductal/acinar involvement to stromal invasion, with or without glandular involvement.

    Purpose of the Study:

    • To analyze the prognostic implications of different prostatic involvement patterns in transitional cell carcinoma of the bladder.
    • To evaluate survival rates based on tumor stage and prostatic invasion characteristics.

    Main Methods:

    • Histopathological review of prostatic tissues in patients with bladder transitional cell carcinoma.
    • Correlation of prostatic invasion patterns with bladder tumor stage and patient survival data.

    Main Results:

    • Invasive prostatic patterns are more common in high-stage bladder tumors, associated with low 5-year survival.

    Related Experiment Videos

  • Non-invasive prostatic patterns correlate with low-stage bladder tumors and better survival.
  • Prostatic stromal invasion, even with low-stage bladder tumors, leads to poor prognosis.

    • Conclusions:

    • Prostatic involvement in bladder cancer has significant prognostic value.
    • Stromal invasion is a critical adverse prognostic factor, though not entirely hopeless.
    • Preoperative radiotherapy followed by cystoprostatourethrectomy may improve survival in select cases.