Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Brainstem CMV encephalitis in AIDS: clinical case and MRI features

F Pierelli1, G Tilia, A Damiani

  • 1Department of Clinical Medicine, University La Sapienza, Rome, Italy.

Neurology
|February 1, 1997
PubMed
Summary

This case study details a patient with acquired immune deficiency syndrome (AIDS) and cytomegalovirus (CMV) encephalitis. MRI revealed primary involvement of posterior fossa structures, presenting with brainstem and cerebellar signs.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Author Correction: Continuous radon monitoring during seven years of volcanic unrest at Campi Flegrei caldera (Italy).

Scientific reports·2026
Same author

Automatic Pipeline for Kinematic Tracking of Clinically Relevant Upper-Limb Motor Tasks in Humans and Macaque.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
Same author

Heat stress disorders and headache: a case of new daily persistent headache secondary to heat stroke.

BMJ case reports·2025
Same author

Covid-19 infection in pregnant women: Auditory evaluation in infants.

Journal of neonatal-perinatal medicine·2024
Same author

The role of lung biopsy for diagnosis and prognosis of interstitial lung disease in systemic sclerosis: a systematic literature review.

Respiratory research·2024
Same author

Italian version of the cornell musculoskeletal discomfort questionnaire (CMDQ-I): Translation, cultural adaptation and validation.

Work (Reading, Mass.)·2021

Area of Science:

  • Neurology
  • Infectious Diseases
  • Radiology

Background:

  • Acquired immune deficiency syndrome (AIDS) can predispose individuals to opportunistic infections affecting the central nervous system.
  • Cytomegalovirus (CMV) encephalitis is a serious opportunistic infection in immunocompromised patients.

Observation:

  • A clinical case of a patient with AIDS and pathologically confirmed CMV encephalitis is presented.
  • The patient exhibited prominent neurological signs localized to the brainstem and cerebellum.
  • Magnetic resonance imaging (MRI) at symptom onset showed significant and nearly exclusive involvement of posterior fossa structures.

Findings:

  • The MRI findings correlated with the clinical presentation of brainstem and cerebellar dysfunction.
  • Pathological confirmation established the diagnosis of cytomegalovirus encephalitis.

Related Experiment Videos

  • The pattern of posterior fossa involvement on MRI was a key diagnostic feature.

    • Implications:

    • This case highlights the importance of considering CMV encephalitis in AIDS patients with posterior fossa neurological deficits.
    • Early recognition of characteristic MRI findings can aid in timely diagnosis and management of CMV encephalitis.
    • Understanding the neuroimaging patterns of opportunistic infections in AIDS is crucial for effective patient care.