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Mucosal immunology and models of mucosal HIV infection
G E Griffin1, L R Castello-Branco, M B Ortigão-de-Sampaio
1Departamento de Imunologia, Instituto Oswaldo Cruz, Rio de Janeiro, Brasil.
Memorias Do Instituto Oswaldo Cruz
|May 1, 1996
Abstract:
The mucosa associated lymphoid tissue regulates and coordinates immune responses against mucosal pathogens. Mucosal tissues are the major targets exposed to HIV during transmission. In this paper we describe in vitro models of HIV mucosal infection using human explants to investigate target cells within this tissue.